Description
NAD+ (Nicotinamide Adenine Dinucleotide) is a foundational cellular coenzyme found in all living cells, essential for systemic metabolic function and cellular viability. This 500mg high-capacity vial provides researchers with a concentrated, premium reagent designed for longitudinal cellular energy and longevity study models.
As a primary electron carrier, NAD+ continuously transitions between its oxidized NAD+ and reduced NADH states. Investigators utilize this reagent to evaluate downstream mechanisms related to mitochondrial biogenesis, DNA repair activation via sirtuins and PARPs, and cellular resistance to oxidative stress.
Key Chemical Specifications
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Chemical Name: Nicotinamide Adenine Dinucleotide (Oxidized Form)
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Molecular Weight: 663.43 g/mol
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CAS Number: 53-84-9
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Quantity: 500 mg
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Form: Lyophilized white powder / cake
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Purity Structure: Greater than or equal to 98% via HPLC analysis
Primary Research Applications
This high-purity 500mg reagent is strictly engineered to support quantitative in vitro and preclinical experimental models, specifically:
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Mitochondrial Homeostasis: Investigating changes in ATP production, cellular respiration, and electron transport chain efficiency.
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Sirtuin & PARP Activation: Studying the regulation of NAD+-dependent enzymes responsible for epigenetic modifications, gene expression, and DNA strand repair cascades.
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Cellular Senescence Models: Analyzing mechanisms to reverse age-related metabolic decline and cellular exhaustion profiles in tissue cultures.
Handling & Storage Guidelines
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Reconstitution: Soluble in sterile Bacteriostatic Water, sterile water, or aqueous buffers. Dissolve with gentle agitation. NAD+ in solution is highly sensitive to rapid degradation if exposed to high temperatures.
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Storage Temperature: Store the dry lyophilized powder long-term at -20°C. Post-reconstitution, store the solution at 2°C to 8°C and utilize within a limited experimental window, or aliquot and freeze immediately to preserve enzymatic stability.
Laboratory Research Disclaimer
This product is synthesized, tested, and distributed strictly for laboratory research,and preclinical scientific investigation only. It is not a medicine, food product, or dietary supplement and is absolutely not intended for human or veterinary consumption, diagnosis, or therapeutic use. Must be handled exclusively by qualified laboratory personnel.
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