2-GLPT

Description

2-GLPT is a prominent synthetic linear peptide containing 39 amino acids, widely utilized in metabolic, glycemic control, and obesity research models. It represents a significant advancement in biochemical evaluation as a dual-acting agonist, selectively targeting both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors.

By engaging both incretin pathways simultaneously, Tirzepatide provides investigators with a highly efficient tool to study multi-receptor signaling crosstalk, integrated metabolic regulation, energy expenditure, and insulin sensitivity profiles in preclinical settings.

Key Chemical Specifications

• Molecular Weight: 4813.45 g/mol

• CAS Number: 2023788-19-2

• Form: Lyophilized white powder / cake

• Purity Structure: Greater than or equal to 98% via HPLC analysis

• Structural Feature: Conjugated to a C20 fatty diacid moiety at the lysine residue (position 20), promoting extended stability and a distinct half-life window for longitudinal in vitro or in vivo study blocks.

Primary Research Applications

Our high-purity Tirzepatide reagent is engineered strictly to support precise laboratory experiments, specifically targeting:

• Incretin Pathway Synergy: Studying the distinct and overlapping cellular contributions of concurrent GIP and GLP-1 receptor activation.

• Metabolic Biomodulation: Investigating changes in lipid metabolism, systemic insulin sensitivity, and glucose handling mechanics.

• Satiety Signalling Models: Analyzing central nervous system signaling pathways related to appetite suppression and delayed gastric emptying models.

Handling & Storage Guidelines

• Reconstitution: Soluble in water or sterile Phosphate-Buffered Saline (PBS). Gentle swirling is recommended; avoid aggressive vortexing to prevent peptide shearing.

• Storage Temperature: Store in a secure, moisture-controlled environment at -20°C for long-term stability. Avoid repeated freeze-thaw cycles by aliquoting into working volumes post-reconstitution.

Laboratory Research Disclaimer

This product is synthesized, tested, and distributed strictly for laboratory research purposes only. It is not a medicine, food product, or dietary supplement and must not be used for human or animal consumption, diagnostic procedures, or any therapeutic application. All purchases must be handled by qualified laboratory personnel using appropriate personal protective equipment.

New to this compound? Read the overview: What Is GLP-2?